Quality and Potency Analysis of IVY Leaf Extract

  • Sidra Yasmeen Faculty of Pharmacy, Jinnah University for women, Karachi, Pakistan
  • Rafia Usman NED University of Engineering and Technology Karachi, Pakistan
  • Sultan Ayaz Department of Eastern Medicine, GC University, Faisalabad, Pakistan
  • Fatima Qamar Faculty of Pharmacy, Jinnah University for women, Karachi, Pakistan
  • Syeda Zainab Faculty of Pharmacy, Jinnah University for women, Karachi, Pakistan
  • Halima Sadia Faculty of Pharmacy, Jinnah University for women, Karachi, Pakistan
  • Hira Munir Research & Development, Herbion Pakistan (Pvt) Limited, Karachi
  • Amaris Arif Research & Development, Herbion Pakistan (Pvt) Limited, Karachi.
  • Sadia Shakeel Faculty of Pharmaceutical Sciences, Dow University of Health Sciences, Karachi
  • Aqib Zahoor Research & Development, Herbion Pakistan (Pvt) Limited, Karachi.
  • Kashifa Khanum Research & Development, Herbion Pakistan (Pvt) Limited, Karachi.
  • Zubair Uddin Faridi Faculty of Pharmacy, Jinnah University for women, Karachi, Pakistan
Keywords: Analysis, Evaluation, Ivy leaf extract, Hederacoside C

Abstract

The current study was conducted with the aim to evaluate Ivy leaf extract to authenticate the quality of extract. Evaluation was conducted on different physicochemical factors of extract that include physical appearance, organoleptic properties and solubility. Loss on drying, microbial analysis and heavy metal analysis was also carried out to execute the safety of extract. High performance liquid chromatography was executed to evaluate the presence of Hederacoside C in Ivy leaf extract employing phosphoric acid 85 %, acetonitrile, water (2:140:860 v/v/v) as a mobile phase. Extract exhibited greenish brown color, distinctive odor and sweet taste. An Ivy extract was found in agreement of the allowable microbial limit as well as with the heavy metal contents limit. The presence of Hederacoside C in Ivy leaf extract was confirmed by HPLC. The current evaluation reveals conformity with all the analytical procedures. Hence Ivy leaf extract is well standardized formulation at the base line consideration.

Published
2020-09-04